Product Name:1-(3-Oxetanyl)-3-azetidinaMine

IUPAC Name:1-(oxetan-3-yl)azetidin-3-amine

CAS:1368005-98-4
Molecular Formula:C6H12N2O
Purity:95%+
Catalog Number:CM106720
Molecular Weight:128.18

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CM106720-1g in stock ȋœŭ

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Product Details

CAS NO:1368005-98-4
Molecular Formula:C6H12N2O
Melting Point:-
Smiles Code:NC1CN(C2COC2)C1
Density:
Catalog Number:CM106720
Molecular Weight:128.18
Boiling Point:
MDL No:
Storage:

Category Infos

Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

Column Infos

Alicyclic Heterocycles
When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.