Product Name:N6-cyclopropyl-9H-purine-2,6-diamine

IUPAC Name:N6-cyclopropyl-9H-purine-2,6-diamine

CAS:120503-69-7
Molecular Formula:C8H10N6
Purity:95%
Catalog Number:CM138661
Molecular Weight:190.21

Packing Unit Available Stock Price($) Quantity
CM138661-250mg in stock ȬƎ
CM138661-1g in stock ǜȬƦ
CM138661-5g in stock NJǜƦ

For R&D use only.

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Product Details

CAS NO:120503-69-7
Molecular Formula:C8H10N6
Melting Point:-
Smiles Code:NC1=NC(NC2CC2)=C3N=CNC3=N1
Density:
Catalog Number:CM138661
Molecular Weight:190.21
Boiling Point:355.9±52.0°C at 760 mmHg
MDL No:MFCD12215664
Storage:Keep in dark place, store at 2-8°C.

Category Infos

Purines
Purines are heterocyclic aromatic compounds composed of linked pyrimidine and imidazole rings. In mammals, purines are most commonly expressed in DNA and RNA (including the purines adenine and guanine), as well as single-molecule nucleotides (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), cyclic AMP, and to a lesser extent guanosine triphosphate (GTP) and cyclic guanosine monophosphate (cGMP). Purines are also key elements of the following energy metabolism molecules: reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate (NADPH), and coenzyme Q. Purines can also act as direct neurotransmitters; for example, adenosine may interact with receptors to modulate cardiovascular and central nervous system (CNS) function.
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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