Product Name:8-Fluoro-10,11-dihydro-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one
IUPAC Name:13-fluoro-7-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-one
| Packing Unit | Available Stock | Price($) | Quantity |
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| CM160889-1g | 1-2 Weeks | ƻƙƻ |
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| Product Overview |
8-Fluoro-10,11-dihydro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one is a small molecule that has been extensively studied in the scientific community for its potential applications in a variety of areas. It is a fluorinated analogue of the pyridinone class of compounds, and its unique structure makes it an attractive target for synthetic organic chemists. |
| Synthesis Method |
8-Fluoro-10,11-dihydro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one can be synthesized using a variety of methods. One of the most commonly used methods is the palladium-catalyzed cross-coupling reaction of a pyridinone derivative and a fluorinated alkyne. This reaction has been used to synthesize 8-fluoro-10,11-dihydro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one in a single step with relatively high yields. Other methods of synthesis include the use of a palladium-catalyzed Suzuki-Miyaura coupling reaction, a palladium-catalyzed Heck reaction, and a palladium-catalyzed Sonogashira coupling reaction. |
| Scientific Research Applications |
8-Fluoro-10,11-dihydro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one is a versatile compound that has been studied for its potential applications in a variety of areas. It has been studied as a potential therapeutic agent for the treatment of cancer, as it has been shown to selectively target and inhibit the activity of the oncogenic protein kinase, AKT1. In addition, 8-Fluoro-10,11-dihydro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one has been studied as a potential tool for the development of novel therapeutic agents, as it has been shown to inhibit the activity of several other proteins, such as the cyclin-dependent kinases, Aurora A and Aurora B. Furthermore, 8-Fluoro-10,11-dihydro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one has been studied as a potential therapeutic agent for the treatment of neurodegenerative diseases, as it has been shown to inhibit the activity of the amyloid-beta peptide, which is known to be involved in the development of Alzheimer’s Disease. |
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