Product Name:(2-(2,4-Dimethylthiazol-5-yl)quinolin-6-yl)boronic acid

IUPAC Name:[2-(2,4-dimethyl-1,3-thiazol-5-yl)quinolin-6-yl]boronic acid

CAS:898825-60-0
Molecular Formula:C14H13BN2O2S
Purity:97%
Catalog Number:CM218474
Molecular Weight:284.14

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Product Details

CAS NO:898825-60-0
Molecular Formula:C14H13BN2O2S
Melting Point:-
Smiles Code:CC1=C(C2=NC3=CC=C(B(O)O)C=C3C=C2)SC(C)=N1
Density:
Catalog Number:CM218474
Molecular Weight:284.14
Boiling Point:
MDL No:
Storage:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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