Product Name:9-(Indolin-1-yl)acridine

IUPAC Name:9-(2,3-dihydro-1H-indol-1-yl)acridine

CAS:139117-65-0
Molecular Formula:C21H16N2
Purity:97%
Catalog Number:CM230806
Molecular Weight:296.37

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Product Details

CAS NO:139117-65-0
Molecular Formula:C21H16N2
Melting Point:-
Smiles Code:C12=NC3=CC=CC=C3C(N4CCC5=C4C=CC=C5)=C1C=CC=C2
Density:
Catalog Number:CM230806
Molecular Weight:296.37
Boiling Point:
MDL No:
Storage:

Category Infos

Indolines
Indoline is an aromatic heterocyclic organic compound with the chemical formula C8H9N. The compound is based on the indole structure, but the 2-3 bond is saturated. Indoles and their derivatives continue to inspire the development of synthetic organic chemistry even years after their discovery. The specific scaffold is a privileged structure and is ubiquitous in pharmaceuticals and biologically active compounds. Fused indolines as indole derivatives are of particular interest as they are often found in natural products and bioactives such as strychnine and tryptanthrins (alkaloids), mitosanes and mitosenes (antitumor activity) and isatisine (antiviral activity).
Acridines
Acridines are organic compounds and nitrogen heterocycles having the formula C13H9N. Acridine is a substituted derivative of the parent ring. It is a planar molecule structurally related to anthracene in which one carbon in the central CH group is replaced by nitrogen. Acridine and its derivatives can be used to make dyes and also used in the pharmaceutical industry. Acridine is a DNA intercalator that easily binds to DNA. Due to its DNA-intercalating properties, acridine or its suitable derivatives are expected to preferentially accumulate in tumors, which are always associated with enhanced DNA replication. Therefore, radiolabeled acridines may have prospect in tumor imaging.

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