Product Name:4-amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

IUPAC Name:4-amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione

CAS:1352827-50-9
Molecular Formula:C14H13N3O4
Purity:95%+
Catalog Number:CM328993
Molecular Weight:287.28

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Product Details

CAS NO:1352827-50-9
Molecular Formula:C14H13N3O4
Melting Point:-
Smiles Code:O=C1N(C(CC2)C(N(C)C2=O)=O)C(C3=C1C=CC=C3N)=O
Density:
Catalog Number:CM328993
Molecular Weight:287.28
Boiling Point:
MDL No:
Storage:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Product Overview 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione, also known as AMPPDI, is a chemical compound that has gained significant attention in the scientific community due to its potential applications in medicinal chemistry.
Synthesis and Application The synthesis of 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione involves the reaction of thalidomide with phthalic anhydride and ammonium acetate in the presence of acetic acid. The resulting compound undergoes a series of purification steps to yield pure 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione. The synthesis of 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione has been extensively studied, and several modifications to the reaction conditions have been proposed to improve the yield and purity of the compound. 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione has been studied for its potential applications in cancer treatment and immunomodulation. Several studies have shown that 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione exhibits potent antitumor activity against a variety of cancer cell lines, including melanoma, breast cancer, and leukemia. The mechanism of action of 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione in cancer cells involves the inhibition of angiogenesis and the induction of apoptosis. 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione has also been shown to enhance the immune response by activating T-cells and natural killer cells.
Future Directions There are several future directions for research on 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione. One potential avenue of research is to investigate the use of 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione in combination with other cancer therapeutics, such as chemotherapy or radiation therapy. Another direction for research is to explore the use of 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione in the treatment of other diseases, such as autoimmune disorders or inflammatory conditions.