Product Name:8-chloro-2-cyclopropylimidazo[1,2-a]pyrazine

IUPAC Name:8-chloro-2-cyclopropylimidazo[1,2-a]pyrazine

CAS:1334167-20-2
Molecular Formula:C9H8ClN3
Purity:95%
Catalog Number:CM168362
Molecular Weight:193.63

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CM168362-1g 1-2 Weeks ƻƏŔ

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Product Details

CAS NO:1334167-20-2
Molecular Formula:C9H8ClN3
Melting Point:-
Smiles Code:ClC1=NC=CN2C1=NC(C3CC3)=C2
Density:
Catalog Number:CM168362
Molecular Weight:193.63
Boiling Point:
MDL No:
Storage:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Imidazopyrazines
In addition to the nitrogen-based heterocycles presented so far, a number of others nitrogen-based scaffolds have also been reported as promising agents for GBM treatment, including pyrazolo-triazole, imidazotetrazine, piperidine, purine, imidazopyrazine, pyrazole, triazole among others.