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① Enzymic reaction
② Carbohydrate chemistry
③ Transition metal-catalyzed coupling reaction
④ Chiral resolution
⑤ Asymmetric catalysis
⑦ High-pressure reaction ( 2000L 10MPa)
⑧ High-temperature reaction（260 ℃）
⑨ Cryogenic reaction（-80 ℃）
⑩ Flow chemistry（Corning flow reactor: nitration, diazotization, continuous ozonization, reaction of unstable compounds and processing)