Product Name:2-Amino-9-(3-hydroxypropoxy)-1H-purin-6(9H)-one

IUPAC Name:2-amino-9-(3-hydroxypropoxy)-6,9-dihydro-1H-purin-6-one

CAS:114778-60-8
Molecular Formula:C8H11N5O3
Purity:97%
Catalog Number:CM246050
Molecular Weight:225.21

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Product Details

CAS NO:114778-60-8
Molecular Formula:C8H11N5O3
Melting Point:-
Smiles Code:O=C1NC(N)=NC2=C1N=CN2OCCCO
Density:
Catalog Number:CM246050
Molecular Weight:225.21
Boiling Point:
MDL No:
Storage:

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Purines
Purines are heterocyclic aromatic compounds composed of linked pyrimidine and imidazole rings. In mammals, purines are most commonly expressed in DNA and RNA (including the purines adenine and guanine), as well as single-molecule nucleotides (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), cyclic AMP, and to a lesser extent guanosine triphosphate (GTP) and cyclic guanosine monophosphate (cGMP). Purines are also key elements of the following energy metabolism molecules: reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate (NADPH), and coenzyme Q. Purines can also act as direct neurotransmitters; for example, adenosine may interact with receptors to modulate cardiovascular and central nervous system (CNS) function.
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Product Overview 2-Amino-9-(3-hydroxypropoxy)-1H-purin-6(9H)-one is an antiviral medication used to treat infections caused by herpes viruses. It was first synthesized in 1977 by Gertrude Elion and George Hitchings at Burroughs Wellcome (now GlaxoSmithKline). 2-Amino-9-(3-hydroxypropoxy)-1H-purin-6(9H)-one is an acyclic guanine nucleoside analog that selectively inhibits viral DNA polymerase, thereby preventing viral replication.
Physical Properties 2-Amino-9-(3-hydroxypropoxy)-1H-purin-6(9H)-one is soluble in DMSO.
Chemical Properties 2-Amino-9-(3-hydroxypropoxy)-1H-purin-6(9H)-one is a reactive compound, often utilized as a starting material or intermediate in various chemical reactions and synthesis processes.
Synthesis and Application 2-Amino-9-(3-hydroxypropoxy)-1H-purin-6(9H)-one has been extensively studied for its antiviral activity against herpes simplex virus (HSV) types 1 and 2, varicella-zoster virus (VZV), and Epstein-Barr virus (EBV). It has also been investigated for its potential use in the treatment of other viral infections, such as cytomegalovirus (CMV) and human immunodeficiency virus (HIV).
Storage and Handling Store 2-Amino-9-(3-hydroxypropoxy)-1H-purin-6(9H)-one at -20°C.