Product Name:tert-Butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate oxalate

IUPAC Name:oxalic acid; tert-butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate

Molecular Formula:C14H24N2O6
Catalog Number:CM105919
Molecular Weight:316.35

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Product Details

CAS NO:1180112-42-8
Molecular Formula:C14H24N2O6
Melting Point:-
Smiles Code:O=C(N(CC1)CCC21CCN2)OC(C)(C)C.O=C(O)C(O)=O
Catalog Number:CM105919
Molecular Weight:316.35
Boiling Point:

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Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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