Product Name:N-(Oxetan-3-yl)piperidin-4-aMine oxalate

IUPAC Name:N-(oxetan-3-yl)piperidin-4-amine; oxalic acid

Molecular Formula:C10H18N2O5
Catalog Number:CM106127
Molecular Weight:246.26

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Product Details

CAS NO:1228948-07-9
Molecular Formula:C10H18N2O5
Melting Point:-
Smiles Code:O=C(O)C(O)=O.C1(NC2COC2)CCNCC1
Catalog Number:CM106127
Molecular Weight:246.26
Boiling Point:

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Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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