Product Name:(4-Chloro-2-fluorophenyl)(6-chloro-2-methyl-8-(morpholinomethyl)-imidazo[1,2-b]pyridazin-3-yl)methanone

IUPAC Name:4-{[6-chloro-3-(4-chloro-2-fluorobenzoyl)-2-methylimidazo[1,2-b]pyridazin-8-yl]methyl}morpholine

CAS:1229236-83-2
Molecular Formula:C19H17Cl2FN4O2
Purity:98%
Catalog Number:CM163249
Molecular Weight:423.27

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Product Details

CAS NO:1229236-83-2
Molecular Formula:C19H17Cl2FN4O2
Melting Point:-
Smiles Code:O=C(C1=CC=C(Cl)C=C1F)C2=C(C)N=C3C(CN4CCOCC4)=CC(Cl)=NN32
Density:
Catalog Number:CM163249
Molecular Weight:423.27
Boiling Point:
MDL No:MFCD23135464
Storage:Store at 2-8°C.

Category Infos

Morpholines
Morpholine contains secondary amine groups and has all the typical reactive characteristics of secondary amine groups. It can react with inorganic acids to form salts, and react with organic acids to form salts or amides, which can be subjected to alkylation reaction, and can also be reacted with ethylene oxide, ketone or Willgerodt reaction. Morpholine is a six-membered ring containing oxygen and nitrogen, and its alkalinity is much lower than that of its parent piperidine. The marketed morpholine drugs are mainly distributed in the fields of tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, digestive system diseases, infectious diseases and mental disorders.
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Imidazopyridazines
Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.