Product Name:tert-butyl 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate

IUPAC Name:tert-butyl 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate

CAS:1234616-51-3
Molecular Formula:C11H18N2O3
Purity:97%
Catalog Number:CM104345
Molecular Weight:226.28

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Product Details

CAS NO:1234616-51-3
Molecular Formula:C11H18N2O3
Melting Point:-
Smiles Code:CC(C)(C)OC(=O)N1CC2(C1)CNC(=O)C2
Density:
Catalog Number:CM104345
Molecular Weight:226.28
Boiling Point:
MDL No:MFCD18325190
Storage:

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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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