Product Name:4-cyclopropyl-1,3-thiazole-5-carboxylic acid

IUPAC Name:4-cyclopropyl-1,3-thiazole-5-carboxylic acid

CAS:1266822-87-0
Molecular Formula:C7H7NO2S
Purity:95%+
Catalog Number:CM464218
Molecular Weight:169.2

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For R&D use only.

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Product Details

CAS NO:1266822-87-0
Molecular Formula:C7H7NO2S
Melting Point:-
Smiles Code:OC(=O)C1=C(N=CS1)C1CC1
Density:
Catalog Number:CM464218
Molecular Weight:169.2
Boiling Point:
MDL No:MFCD19282048
Storage:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.