Product Name:4,4,5,5-tetramethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolane

IUPAC Name:4,4,5,5-tetramethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolane

CAS:126726-62-3
Molecular Formula:C9H17BO2
Purity:96%
Catalog Number:CM100150
Molecular Weight:168.04

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CM100150-1000g in stock œǺǺ

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Product Details

CAS NO:126726-62-3
Molecular Formula:C9H17BO2
Melting Point:-
Smiles Code:C=C(B1OC(C)(C)C(C)(C)O1)C
Density:
Catalog Number:CM100150
Molecular Weight:168.04
Boiling Point:
MDL No:MFCD08276843
Storage:

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Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Sotorasib
Dec. 26, 2023, Amgen announced that the U.S. FDA has completed its review of the company's supplemental New Drug Application seeking full approval of LUMAKRAS (sotorasib).
LUMAKRAS (sotorasib) is an oral, first-in-class therapy indicawithted for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC) following at least one previous systemic therapy.
Sotorasib is the first approved targeted therapy for patients with tumors with any KRAS mutation, which accounts for approximately 25% of mutations in NSCLC. The U.S. FDA granted the application for sotorasib orphan drug, fast track, priority review, and breakthrough therapy designations.
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