Product Name:6-amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one
IUPAC Name:6-amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one
Product Overview |
6-Amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one, also known as AME-DHP, is a pyrimidine derivative. |
Synthesis Method |
The synthesis of 6-Amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one involves the condensation of ethyl acetoacetate with guanidine hydrochloride in the presence of sodium ethoxide. This reaction yields 6-Amino-2-ethyl-5-methyl-4-hydroxypyrimidine, which is further reacted with acetic anhydride to form the final product, 6-Amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one. |
Chemical Properties |
One of the advantages of using 6-Amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one in lab experiments is its relatively simple synthesis method, which allows for easy production of the compound. |
Synthesis and Application |
The compound has shown promising results in various preclinical studies, including its ability to inhibit the growth of cancer cells, reduce inflammation, and act as an antifungal agent. Additionally, 6-Amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one has shown neuroprotective effects and has been studied for its potential use in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. |
Future Directions |
One potential direction is the further investigation of its mechanism of action, which may provide insight into its potential therapeutic applications. Additionally, the compound's neuroprotective effects warrant further study for its potential use in the treatment of neurodegenerative diseases. Finally, the development of analogs of 6-Amino-2-ethyl-5-methyl-3,4-dihydropyrimidin-4-one may lead to the discovery of more potent and selective compounds with improved therapeutic potential. |