Product Name:2-(3-(Trifluoromethyl)phenyl)azepane hydrochloride

IUPAC Name:2-[3-(trifluoromethyl)phenyl]azepane hydrochloride

CAS:1346602-95-6
Molecular Formula:C13H17ClF3N
Purity:97%
Catalog Number:CM291754
Molecular Weight:279.73

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Product Details

CAS NO:1346602-95-6
Molecular Formula:C13H17ClF3N
Melting Point:-
Smiles Code:FC(C1=CC(C2NCCCCC2)=CC=C1)(F)F.[H]Cl
Density:
Catalog Number:CM291754
Molecular Weight:279.73
Boiling Point:
MDL No:
Storage:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Azepanes
The use of azepane as a scaffold for drug discovery remains of interest. The azepane linker is the key to efficient activity. A number of seven-membered ring derivatives have been prepared or investigated for their potential or actual pharmacological properties. Examples include azaalkane derivatives as PKB (protein kinase B) inhibitors.

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