Product Name:2-Amino-7-(1-hydroxypropan-2-yl)-1H-purin-6(7H)-one
IUPAC Name:2-amino-7-(1-hydroxypropan-2-yl)-6,7-dihydro-1H-purin-6-one
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| Product Overview |
7-(1-Methyl-2-hydroxyethyl)guanine, also known as MheG, is a modified nucleoside that has been found to have potential applications in scientific research. |
| Synthesis Method |
7-(1-Methyl-2-hydroxyethyl)guanine is synthesized through a multistep process that involves the reaction of guanine with formaldehyde and sodium cyanoborohydride. The resulting compound is then treated with methyl iodide and hydroxide to form 7-(1-Methyl-2-hydroxyethyl)guanine. This synthesis method has been optimized to produce high yields of 7-(1-Methyl-2-hydroxyethyl)guanine with minimal impurities. |
| Chemical Properties |
7-(1-Methyl-2-hydroxyethyl)guanine has some limitations, including its potential toxicity and the difficulty of synthesizing large quantities of pure 7-(1-Methyl-2-hydroxyethyl)guanine. |
| Synthesis and Application |
This compound has been found to have unique properties that make it useful for studying the structure and function of nucleic acids. For example, 7-(1-Methyl-2-hydroxyethyl)guanine has been used as a probe to study the structure of DNA and RNA, as well as to investigate the interactions between nucleic acids and proteins. |
| Future Directions |
One area of interest is the development of new synthetic methods for producing 7-(1-Methyl-2-hydroxyethyl)guanine with higher yields and purity. Another potential direction is the investigation of the therapeutic potential of 7-(1-Methyl-2-hydroxyethyl)guanine in cancer treatment, particularly in combination with other drugs. Additionally, further studies are needed to fully understand the mechanism of action of 7-(1-Methyl-2-hydroxyethyl)guanine and its effects on gene expression and other cellular processes. |
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