Product Name:[1-(Cyclobutylmethyl)-1H-indazol-5-yl]boronic acid

IUPAC Name:[1-(cyclobutylmethyl)-1H-indazol-5-yl]boronic acid

CAS:1357918-08-1
Molecular Formula:C12H15BN2O2
Purity:95%+
Catalog Number:CM561689
Molecular Weight:230.07

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CM561689-1g 1-2 Weeks Ʃƅœœ

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Product Details

CAS NO:1357918-08-1
Molecular Formula:C12H15BN2O2
Melting Point:-
Smiles Code:OB(C1=CC2=C(N(CC3CCC3)N=C2)C=C1)O
Density:
Catalog Number:CM561689
Molecular Weight:230.07
Boiling Point:
MDL No:
Storage:2-8°C

Category Infos

Indazoles
Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.
Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.

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