Product Name:2-oxo-N-[2-(pyrrolidin-1-yl)pyrimidin-5-yl]-2H-chromene-3-carboxamide

IUPAC Name:2-oxo-N-[2-(pyrrolidin-1-yl)pyrimidin-5-yl]-2H-chromene-3-carboxamide

CAS:1396746-42-1
Molecular Formula:C18H16N4O3
Purity:95%+
Catalog Number:CM855112
Molecular Weight:336.35

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Product Details

CAS NO:1396746-42-1
Molecular Formula:C18H16N4O3
Melting Point:-
Smiles Code:O=C(NC1=CN=C(N=C1)N1CCCC1)C1=CC2=CC=CC=C2OC1=O
Density:
Catalog Number:CM855112
Molecular Weight:336.35
Boiling Point:
MDL No:
Storage:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Coumarins
Coumarin occurs naturally in a variety of plants, such as lentils, sweet sawdust, vanilla grass, and sweet grass. Coumarin has a simple structure, benzopyrone, associated with different reaction centers. Coumarins are further subdivided into different classes: simple coumarins, pyranocoumarins, furanocoumarins, dicoumarins and isocoumarins. Coumarin derivatives are an important class of natural plant metabolites with various biological activities. They can also be synthesized artificially, and various synthetic coumarin derivatives (azoles, sulfonyls, furans, pyrazoles, etc.) have shown good anticancer, antitumor and antiproliferative activities. Coumarin derivatives are not only effective anticancer agents, but also possess minimum side effects. Based on different substitution patterns, these potential active substances show a great ability to modulate potential anticancer activities.

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