Product Name:N-propyl-3-(1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl)imidazo[1,2-b]pyridazin-6-amine

IUPAC Name:3-[1-(oxan-2-yl)-1H-indazol-5-yl]-N-propylimidazo[1,2-b]pyridazin-6-amine

CAS:1431698-03-1
Molecular Formula:C21H24N6O
Purity:95%+
Catalog Number:CM330788
Molecular Weight:376.45

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CM330788-100mg in stock ƦƦư
CM330788-250mg in stock ƀǜƎ
CM330788-1g 1-2 Weeks ȺȬưNJ

For R&D use only.

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Product Details

CAS NO:1431698-03-1
Molecular Formula:C21H24N6O
Melting Point:-
Smiles Code:CCCNC(C=C1)=NN2C1=NC=C2C3=CC4=C(N(C5CCCCO5)N=C4)C=C3
Density:
Catalog Number:CM330788
Molecular Weight:376.45
Boiling Point:
MDL No:
Storage:2-8°C

Category Infos

Indazoles
Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.
Tetrahydropyrans
Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.
Imidazopyridazines
Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.

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