Product Name:tert-butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate

IUPAC Name:tert-butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate

Molecular Formula:C11H19NO3
Catalog Number:CM104348
Molecular Weight:213.28

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Product Details

CAS NO:147804-30-6
Molecular Formula:C11H19NO3
Melting Point:-
Smiles Code:CC(C)(C)OC(=O)N1CCC2(CO2)CC1
Catalog Number:CM104348
Molecular Weight:213.28
Boiling Point:
MDL No:MFCD07779385

Category Infos

Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Oxirane is a three-membered ring compound consisting of one oxygen atom and two carbon atoms. Oxirane is present in natural products such as cryptocin, which has anticancer properties, and azidomycin, trienone, and epoxidomycin, which have shown activity against drug-resistant leukemias and AIDS-related lymphomas. Other oxirane containing bioactive molecules have anti-inflammatory, immunosuppressive, and antitumor activities. Oxiranes are a strained ring susceptible to various nucleophilic, ring-opening or rearrangement reactions, so they are considered to be one of the most important intermediates in organic synthesis.

Column Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.

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