Product Name:tert-butyl 3-[(oxetan-3-yl)amino]azetidine-1-carboxylate

IUPAC Name:tert-butyl 3-[(oxetan-3-yl)amino]azetidine-1-carboxylate

CAS:1519689-69-0
Molecular Formula:C11H20N2O3
Purity:95%+
Catalog Number:CM648065
Molecular Weight:228.29

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Product Details

CAS NO:1519689-69-0
Molecular Formula:C11H20N2O3
Melting Point:-
Smiles Code:CC(C)(C)OC(=O)N1CC(C1)NC1COC1
Density:
Catalog Number:CM648065
Molecular Weight:228.29
Boiling Point:
MDL No:MFCD23839094
Storage:

Category Infos

Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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