cas 1620056-83-8|| where to buy 2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetic acid

Product Name:2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetic acid

IUPAC Name:2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl)-7,8-diazatricyclo[4.3.0.0²,⁴]nona-1(6),8-dien-7-yl]acetic acid

: CAS：1620056-83-8; Molecular Formula：C10H7F5N2O2; Purity：97%

: Catalog Number：CM545799; Molecular Weight：282.17

Packing Unit	Available Stock	Price($)	Quantity
CM545799-1000g	in stock	ŪȅȖƐǑ

Inquiry: sales@chemenu.com

For R&D use only.

Inquiry Form

Chemical Name

CAS Number

Quantity*

Required Specifications*
(Assay %, Material Grade etc.)

Contact Name*

Contact Email*

Additional Notes

Verification code*

refresh

Product Details

: CAS NO:1620056-83-8; Molecular Formula:C10H7F5N2O2; Melting Point:-; Smiles Code:OC(=O)CN1N=C(C2=C1C(F)(F)[C@@H]1C[C@H]21)C(F)(F)F; Density:

: Catalog Number:CM545799; Molecular Weight:282.17; Boiling Point:; MDL No:; Storage:

Category Infos

: Pyrazoles; Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.; Pyrazone; Custom pyrazone for customers from all over the world are our main business.

: Fluorinated Compounds; Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

Column Infos

: Islatravir and Lenacapavir; Gilead and Merck announced results from the Phase 2 clinical study evaluating the investigational combination of islatravir, an investigational nucleoside reverse transcriptase translocation inhibitor, and lenacapavir, a first-in-class , long-acting HIV capsid inhibitor. At 24 weeks, the novel investigational combination maintained a high rate (94.2%) of viral suppression (HIV-1 RNA <50 copies/mL), which is a secondary endpoint of the study. Results of the primary endpoint (HIV-1 RNA ≥50 copies/mL (c/mL) showed that one participant (1.9%) treated with islatravir and lenacapavir had a viral load of >50 copies/mL at Week 24;the participant later suppressed on islatravir and lenacapavir at Week 30.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.

Related Products

2724-56-3

56305-04-5

89663-86-5

27610-92-0

928-17-6

118021-35-5

1951-38-8

337493-89-7

19360-67-9

103-46-8

212757-14-7

50826-72-7

93748-19-7

882500-52-9

935478-29-8

30033-24-0

165105-47-5

294858-41-6

2268819-82-3

111223-31-5

2171765-46-9

13423-73-9

1855-28-3

99863-59-9

334018-32-5

81170-13-0

614-81-3

1603580-85-3

500695-54-5

103854-25-7

1694614-97-5

777-66-2

334018-28-9

32404-28-7

87113-22-2

1956311-00-4

77290-43-8

2339-98-2

1342425-67-5

91819-11-3

20370-80-3

62499-04-1

1785030-01-4

1037423-77-0

1270307-81-7

65399-12-4

1270315-04-2

116435-35-9

439587-17-4

318270-11-0

299169-13-4

261762-99-6

1820648-21-2

64913-50-4

1698027-17-6

204138-23-8

114622-81-0

426837-11-8

1272755-68-6

61008-98-8

853908-26-6

228107-54-8

2323574-78-1

1221964-50-6

528-46-1

1379664-88-6

74590-68-4

56145-94-9

21739-97-9

2138193-88-9

855202-79-8

62268-16-0

959762-87-9

16110-99-9

402-87-9

62268-15-9

25641-98-9

197153-87-0

1585-67-7

649770-58-1

101033-03-8

56962-06-2

4165-96-2

66056-40-4

1352275-74-1

26539-01-5

106518-44-9

21977-42-4

51552-86-4

7735-38-8

1159823-43-4

1143519-21-4

2410594-75-9

1250986-82-3

1423116-90-8

1258826-86-6

2410594-60-2

1203543-98-9

943119-34-4

1447944-00-4

2227762-87-8

775280-49-4

1627965-05-2

1993276-98-4

1013794-57-4

895126-65-5

1311315-21-5

956935-28-7

1042629-06-0

1394023-51-8

871257-83-9

2097854-07-2

1343405-76-4

2055043-60-0

911635-43-3

127980-13-6

2227198-82-3

617-68-5

4090-17-9

20986-22-5

19525-59-8

143-18-0

15968-01-1

15467-20-6

143-19-1

30377-07-2

137-16-6

822-12-8

408-35-5

77305-02-3

79704-35-1

26060-56-0

66749-60-8

19538-71-7

36290-94-5

180798-01-0

76769-55-6

192124-66-6

1999-46-8

2279-16-5

35436-83-0

56217-82-4

4337-37-5

615-82-7

1999-42-4

688-12-0

3588-60-1

1115-24-8

2159-42-4

23082-12-4

6385-02-0

24173-43-1

59160-29-1

21691-43-0

63245-28-3

67206-26-2

1067-33-0

616-05-7

1504-41-2

2623-82-7

59662-48-5

58573-94-7

25354-97-6

14936-66-4

593-39-5

97-78-9

7596-88-5

1961-72-4

629-56-1

2190-04-7

1462-52-8

5519-23-3

69367-32-4

135447-09-5

377085-56-8

17635-44-8

847818-74-0

344591-91-9

96145-98-1

199003-22-0

214614-81-0

82231-53-6

102846-11-7

75092-30-7

1146637-10-6

552846-17-0

957035-33-5

943541-20-6

847818-79-5

850349-20-1

1449117-30-9

374064-02-5

903550-26-5

761446-44-0

178424-17-4

141302-33-2

1003846-21-6

1029716-44-6

269410-08-4

39806-90-1

5932-34-3

1046832-21-6

100852-80-0

192711-20-9

1033805-26-3

917900-37-9

1362243-50-2

850349-24-5

1002309-48-9

1007110-53-3

1029715-63-6

1040377-03-4

1040377-08-9

1040377-18-1

1047644-76-7

1082503-77-2

1152858-54-2

1189746-27-7

1204580-79-9

1242336-77-1

1253912-00-3

1282518-60-8

1297546-22-5

1339890-99-1