Product Name:3-(4-(Trifluoromethyl)phenyl)oxetane-3-carboxylic acid

IUPAC Name:3-[4-(trifluoromethyl)phenyl]oxetane-3-carboxylic acid

CAS:1894778-31-4
Molecular Formula:C11H9F3O3
Purity:95%+
Catalog Number:CM625865
Molecular Weight:246.19

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Product Details

CAS NO:1894778-31-4
Molecular Formula:C11H9F3O3
Melting Point:-
Smiles Code:OC(=O)C1(COC1)C1=CC=C(C=C1)C(F)(F)F
Density:
Catalog Number:CM625865
Molecular Weight:246.19
Boiling Point:
MDL No:
Storage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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