Product Name:1-cyclobutyl-2,2-difluorocyclopropane-1-carboxylic acid

IUPAC Name:1-cyclobutyl-2,2-difluorocyclopropane-1-carboxylic acid

CAS:2229595-48-4
Molecular Formula:C8H10F2O2
Purity:95%+
Catalog Number:CM464234
Molecular Weight:176.16

Packing Unit Available Stock Price($) Quantity
CM464234-250mg 4-5 Weeks NJưŹ
CM464234-500mg 5-6 Weeks ůŹĽǤ
CM464234-1g 5-6 Weeks ůǤNJȎ

For R&D use only.

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Product Details

CAS NO:2229595-48-4
Molecular Formula:C8H10F2O2
Melting Point:-
Smiles Code:OC(=O)C1(CC1(F)F)C1CCC1
Density:
Catalog Number:CM464234
Molecular Weight:176.16
Boiling Point:
MDL No:MFCD31718473
Storage:

Category Infos

Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.