Product Name:7-Chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

IUPAC Name:7-chloro-6-fluoro-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

CAS:2252403-82-8
Molecular Formula:C16H14ClFN4O2
Purity:95%+
Catalog Number:CM337558
Molecular Weight:348.76

Packing Unit Available Stock Price($) Quantity
CM337558-100g in stock Žǟijij
CM337558-500g in stock ijǸřħ
CM337558-1000g in stock ƚřřř

For R&D use only.

Inquiry Form

   refresh    

Product Details

CAS NO:2252403-82-8
Molecular Formula:C16H14ClFN4O2
Melting Point:-
Smiles Code:O=C1N(C2=C(C)C=CN=C2C(C)C)C3=NC(Cl)=C(F)C=C3C(N1)=O
Density:
Catalog Number:CM337558
Molecular Weight:348.76
Boiling Point:
MDL No:
Storage:Keep in a tight container and store at abient temperature

Category Infos

Column Infos

Sotorasib
Dec. 26, 2023, Amgen announced that the U.S. FDA has completed its review of the company's supplemental New Drug Application seeking full approval of LUMAKRAS (sotorasib).
LUMAKRAS (sotorasib) is an oral, first-in-class therapy indicawithted for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC) following at least one previous systemic therapy.
Sotorasib is the first approved targeted therapy for patients with tumors with any KRAS mutation, which accounts for approximately 25% of mutations in NSCLC. The U.S. FDA granted the application for sotorasib orphan drug, fast track, priority review, and breakthrough therapy designations.