Product Name:5-Formyl-4-methyl-1-[(2S)-2-[4-(methylsulfonyl)-1-piperazinyl]propyl]-1H-indole-2-carbonitrile

IUPAC Name:5-formyl-1-[(2S)-2-(4-methanesulfonylpiperazin-1-yl)propyl]-4-methyl-1H-indole-2-carbonitrile

CAS:2437331-14-9
Molecular Formula:C19H24N4O3S
Purity:95%+
Catalog Number:CM1075328
Molecular Weight:388.49

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Product Details

CAS NO:2437331-14-9
Molecular Formula:C19H24N4O3S
Melting Point:-
Smiles Code:C([C@H](C)N1CCN(S(C)(=O)=O)CC1)N2C=3C(C=C2C#N)=C(C)C(C=O)=CC3
Density:
Catalog Number:CM1075328
Molecular Weight:388.49
Boiling Point:
MDL No:
Storage:

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Indoles
Indole is a compound of pyrrole and benzene in parallel, also known as benzopyrrole. There are two combinations of pyrrole and benzene, called indole and isoindole, respectively. Many derivatives of indole have physiological and pharmacological activities, and can synthesize vasodilators, antihistamines, antipyretic analgesics, etc. in medicine, so indole is also a very important heterocyclic compound.
indole company
As a indole company,we sincerely welcome the new and old friends from home and abroad to synergize with our company and share the benefits and opportunities.

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Ziftomenib
Kura Oncology reported preliminary clinical data from the first 20 patients in KOMET-007, a Phase 1 dose-escalation trial of the Company's potent and selective menin inhibitor, ziftomenib, in combination with standards of care, including cytarabine/daunorubicin (7+3) and venetoclax/azacitidine (ven/aza), in patients with NPM1-mutant (NPM1-m) and KMT2A-rearranged (KMT2A-r) acute myeloid leukemia (AML). Ziftomenib is a novel, once-daily, oral investigational drug candidate targeting the menin-KMT2A/MLL protein-protein interaction for treatment of genetically defined AML patients with high unmet need. In preclinical models, ziftomenib inhibits the KMT2A/MLL protein complex and exhibits downstream effects on HOXA9/MEIS1 expression and potent anti-leukemic activity in genetically defined preclinical models of AML. Ziftomenib has received Orphan Drug Designation from the FDA for the treatment of AML.
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