Product Name:Methyl 6-bromo-4-hydroxyquinoline-2-carboxylate

IUPAC Name:methyl 6-bromo-4-oxo-1,4-dihydroquinoline-2-carboxylate

CAS:262586-62-9
Molecular Formula:C11H8BrNO3
Purity:95%+
Catalog Number:CM143638
Molecular Weight:282.09

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Product Details

CAS NO:262586-62-9
Molecular Formula:C11H8BrNO3
Melting Point:-
Smiles Code:O=C(C(NC1=C2C=C(Br)C=C1)=CC2=O)OC
Density:
Catalog Number:CM143638
Molecular Weight:282.09
Boiling Point:
MDL No:MFCD10001494
Storage:Store at 2-8°C.

Category Infos

Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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Product Overview Methyl 6-bromo-4-hydroxyquinoline-2-carboxylate is a chemical compound that has gained significant attention in recent years due to its potential applications in scientific research. This compound is a derivative of quinoline, which is a heterocyclic aromatic organic compound that has been extensively studied for its biological and pharmacological properties. Methyl 6-bromo-4-hydroxyquinoline-2-carboxylate has been synthesized using various methods and has been evaluated for its mechanism of action, biochemical and physiological effects, advantages, and limitations for lab experiments.
Synthesis and Application Methyl 6-bromo-4-hydroxyquinoline-2-carboxylate can be synthesized using various methods. One of the most common methods involves the reaction of 6-bromo-2-hydroxyquinoline with methyl chloroformate in the presence of a base such as triethylamine. The reaction is carried out under reflux conditions for several hours, and the product is obtained by filtration and purification. Other methods involve the use of different reagents and conditions, such as the reaction of 6-bromo-2-chloroquinoline with methyl 2-hydroxybenzoate in the presence of a palladium catalyst. Methyl 6-bromo-4-hydroxyquinoline-2-carboxylate has been evaluated for its potential applications in scientific research. One of the significant applications of this compound is in the field of cancer research. It has been shown to exhibit potent cytotoxic activity against various cancer cell lines, including breast, lung, and colon cancer. The compound has been found to induce apoptosis in cancer cells by activating the intrinsic pathway of apoptosis. It has also been shown to inhibit the growth and proliferation of cancer cells by inducing cell cycle arrest at the G2/M phase.
Future Directions Methyl 6-bromo-4-hydroxyquinoline-2-carboxylate has several potential future directions in scientific research. One of the significant future directions is the development of novel anticancer drugs based on the structure of this compound. The compound can be used as a lead compound for the development of more potent and selective anticancer drugs. Another future direction is the evaluation of the compound's potential applications in other areas of scientific research, such as infectious diseases and neurodegenerative disorders. The compound's mechanism of action can be studied in more detail to identify new cellular targets and pathways that can be targeted for therapeutic purposes. The compound's physicochemical properties can also be optimized to improve its solubility and stability, which can enhance its potential applications in various research areas.