Product Name:10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride
IUPAC Name:9-methoxy-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,9,11,13-heptaene-2-carbonyl chloride
Product Overview |
10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride is a chemical compound that is widely used in scientific research. It is a derivative of clozapine, which is an atypical antipsychotic drug used to treat schizophrenia. 10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride is a valuable tool for studying the function of G protein-coupled receptors (GPCRs) in the brain and other tissues. |
Physical Properties |
10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride is a light yellow or almost white crystalline powder. |
Chemical Properties |
10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride is a reactive compound, often utilized as a starting material or intermediate in various chemical reactions and synthesis processes. |
Synthesis and Application |
10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride is widely used in scientific research to study the function of GPCRs. GPCRs are a large family of membrane proteins that play crucial roles in cell signaling and are targets for many drugs. 10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride is a selective agonist for the Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), which are engineered GPCRs that can be selectively activated by 10-methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride. DREADDs are used to study the function of specific cell types or circuits in the brain and other tissues. 10-Methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride is also used to study the function of other GPCRs, such as the muscarinic acetylcholine receptors and the serotonin receptors. |
Storage and Handling |
Store 10-methoxy-5H-dibenzo[b,f]azepine-5-carbonyl chloride at 2-8°C. |