Product Name:(S)-2-Amino-2-cyclopropylacetic acid

IUPAC Name:(2S)-2-amino-2-cyclopropylacetic acid

Molecular Formula:C5H9NO2
Catalog Number:CM100562
Molecular Weight:115.13

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CM100562-5g in stock Ƽdž

For R&D use only.

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Product Details

CAS NO:49606-99-7
Molecular Formula:C5H9NO2
Melting Point:-
Smiles Code:O=C(O)[C@@H](N)C1CC1
Catalog Number:CM100562
Molecular Weight:115.13
Boiling Point:253.5°C at 760 mmHg
MDL No:MFCD06659116
Storage:Store at room temperature.

Category Infos

Amino Acids and Peptides
Amino acids are organic compounds containing a basic amino group and an acidic carboxyl group. Because amino acids contain both amino and carboxyl groups, they can be polymerized in an end-to-end manner, removing a molecule of water to form a covalent amide bond or peptide bond. Many amino acids are linked together end to end to form a polypeptide. Amino acids and peptides are important components in the fields of medicine and life sciences.
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Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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Product Other Information

Product Overview L-Cyclopropylglycine (L-CPG) is an amino acid that has been studied extensively for its use in a variety of scientific research applications.
Synthesis Method L-Cyclopropylglycine is synthesized from the reaction of cyclopropylglycine methyl ester and sodium hydroxide in aqueous solution. The reaction yields a racemic mixture of L-Cyclopropylglycine and D-CPG, which can then be separated through chromatography. Several other methods have been developed for the synthesis of L-Cyclopropylglycine, including the use of a Wittig reaction, a Sharpless asymmetric dihydroxylation, and a Sharpless asymmetric epoxidation.
Synthesis and Application It is relatively inexpensive and easy to synthesize, and can be used as a chiral amino acid in a variety of laboratory experiments. It is not very stable in aqueous solutions, and is susceptible to hydrolysis and oxidation. In addition, L-Cyclopropylglycine can be difficult to purify, and can be difficult to separate from other compounds. L-Cyclopropylglycine has been used in a variety of scientific research applications, including drug discovery, biochemistry, and protein engineering. It has been used to study the effects of chirality on the binding of drugs to their target proteins, as well as to study the effects of chirality on enzyme activity. In addition, L-Cyclopropylglycine has been used to study the effects of chirality on the structure and function of proteins, and to study the effects of chirality on the folding of proteins.
Future Directions Further studies could be conducted to explore the effects of chirality on the structure and function of proteins and enzymes. In addition, further studies could be conducted to explore the effects of chirality on the binding of drugs to their target proteins. Finally, further studies could be conducted to explore the potential therapeutic applications of L-Cyclopropylglycine, such as the use of L-Cyclopropylglycine as a therapeutic agent for the treatment of a variety of diseases.