Product Name:6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS)

IUPAC Name:2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate

CAS:55750-63-5
Molecular Formula:C14H16N2O6
Purity:95%+
Catalog Number:CM328887
Molecular Weight:308.29

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CM328887-50mg in stock ǯǕ
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CM328887-500mg in stock ŢƞƄ

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Product Details

CAS NO:55750-63-5
Molecular Formula:C14H16N2O6
Melting Point:-
Smiles Code:O=C(ON1C(CCC1=O)=O)CCCCCN2C(C=CC2=O)=O
Density:
Catalog Number:CM328887
Molecular Weight:308.29
Boiling Point:480.6°C at 760 mmHg
MDL No:MFCD00043043
Storage:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Pyrrolines
Pyrrolines, also called dihydropyrroles, are obtained from aromatic pyrroles by hydrogenation. 1-pyrroline is a cyclic imine, while 2-pyrroline and 3-pyrroline are cyclic amines.
ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.

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