Product Name:8-Methyl-2-oxo-2H-chromene-3-carboxylic acid
IUPAC Name:8-methyl-2-oxo-2H-chromene-3-carboxylic acid
| Packing Unit | Available Stock | Price($) | Quantity |
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| CM285773-250mg | in stock | Ȗƚ |
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| CM285773-1g | in stock | dždžƚ |
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| Product Overview |
8-Methyl-2-oxo-2H-chromene-3-carboxylic acid, also known as coumarin-3-carboxylic acid, is a naturally occurring compound found in many plants. It has been studied for its various biological activities and has shown potential in the field of medicinal chemistry. |
| Synthesis and Application |
8-Methyl-2-oxo-2H-chromene-3-carboxylic acid can be synthesized through various methods, including the Pechmann condensation reaction and the Knoevenagel reaction. The Pechmann condensation reaction involves the reaction of salicylaldehyde with an acid catalyst to form 7-hydroxycoumarin, which is then further reacted with methyl iodide to form 7-methoxycoumarin. The Knoevenagel reaction involves the reaction of salicylaldehyde with malonic acid in the presence of a base catalyst to form 8-Methyl-2-oxo-2H-chromene-3-carboxylic acidarboxylic acid. Both methods have been used to synthesize 8-Methyl-2-oxo-2H-chromene-3-carboxylic acid with high yields. 8-Methyl-2-oxo-2H-chromene-3-carboxylic acid has been studied for its various biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. It has also shown potential in the field of medicinal chemistry, particularly in the development of anticancer agents. Studies have shown that 8-Methyl-2-oxo-2H-chromene-3-carboxylic acid can induce apoptosis in cancer cells by activating caspase-3 and caspase-9 pathways. It has also been shown to inhibit the growth of various cancer cell lines, including breast, lung, and colon cancer cells. |
| Future Directions |
There are several future directions for the research of 8-Methyl-2-oxo-2H-chromene-3-carboxylic acid. One area of interest is the development of novel anticancer agents based on its structure and mechanism of action. Another area of interest is the investigation of its potential in the treatment of inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. |
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