Product Name:4-Quinazolinamine, 6-(3-aminopropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxy-

IUPAC Name:6-(3-aminopropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine

CAS:655247-75-9
Molecular Formula:C18H18ClFN4O2
Purity:95%+
Catalog Number:CM633422
Molecular Weight:376.82

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CM633422-250mg in stock ľǪůIJ
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For R&D use only.

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Product Details

CAS NO:655247-75-9
Molecular Formula:C18H18ClFN4O2
Melting Point:-
Smiles Code:COC1=CC2=NC=NC(NC3=CC(Cl)=C(F)C=C3)=C2C=C1OCCCN
Density:
Catalog Number:CM633422
Molecular Weight:376.82
Boiling Point:
MDL No:
Storage:

Category Infos

Quinazolines
Quinazolines belong to heterocyclic chemistry, also known as 1,3-naphthalenes. The backbone consists of two six-membered aromatic rings fused to each other, with two nitrogen atoms at positions 1 and 3 on the backbone. The presence of these two nitrogen atoms in quinazoline increases its importance in pharmaceutical and biological reactions. Quinazolines and their derivatives are among the most important heterocyclic compounds due to their diverse chemical reactivity and important range of biological activities.


Product Other Information

Product Overview Linkable gefitinib analogue (LGA) is a novel drug developed by scientists to target cancer cells. It is a derivative of gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, which has been used to treat non-small cell lung cancer (NSCLC). LGA is designed to be more effective than gefitinib in targeting cancer cells and has been studied extensively in laboratory experiments.
Synthesis and Application The synthesis of Linkable gefitinib analogue involves a series of chemical reactions. First, gefitinib is reacted with a linker molecule, such as a cyclic anhydride or a thiol-containing compound, which forms an amide or thioester bond. This bond is then reacted with a target molecule, such as an antibody or a peptide, to form a covalent bond. Finally, the linker molecule is cleaved, releasing the Linkable gefitinib analogue molecule. This method has been used to synthesize various derivatives of gefitinib, including Linkable gefitinib analogue. Linkable gefitinib analogue has been studied extensively in laboratory experiments to determine its efficacy in targeting cancer cells. It has been used in a variety of cell-based assays to test the effects of the drug on tumor cell proliferation, invasion, and migration. It has also been used in animal models to study the drug’s effects on tumor growth and metastasis. Additionally, Linkable gefitinib analogue has been used in clinical trials to evaluate its efficacy in treating NSCLC.
Future Directions There are several potential future directions for the use of Linkable gefitinib analogue. It could be used in combination with other drugs to further enhance its efficacy in targeting cancer cells. Additionally, it could be used in combination with immunotherapies to target tumor cells more effectively. Furthermore, it could be used in combination with other drugs to target other types of cancer, such as breast, ovarian, and colorectal cancer. Finally, it could be used to target other types of diseases, such as autoimmune disorders and neurological diseases.