Product Name:5,8-Dimethoxyquinolin-2(1H)-one

IUPAC Name:5,8-dimethoxy-1,2-dihydroquinolin-2-one

CAS:79784-30-8
Molecular Formula:C11H11NO3
Purity:95%+
Catalog Number:CM411478
Molecular Weight:205.21

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Product Details

CAS NO:79784-30-8
Molecular Formula:C11H11NO3
Melting Point:-
Smiles Code:COC1=C2NC(=O)C=CC2=C(OC)C=C1
Density:
Catalog Number:CM411478
Molecular Weight:205.21
Boiling Point:
MDL No:MFCD19678318
Storage:

Category Infos

Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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Product Other Information

Product Overview 5,8-Dimethoxyquinolin-2(1H)-one, commonly known as DMQ, is a naturally occurring quinolinone derived from the root of the Chinese medicinal herb, Stephania tetrandra. It is a potent anti-inflammatory, anti-oxidant, and anti-tumor agent, and has been studied for its potential therapeutic applications in a variety of diseases. DMQ has been found to be effective in treating several types of cancer, including lung, breast, and colon cancer, as well as chronic inflammation and oxidative stress. In addition, DMQ has been studied for its potential to inhibit the growth of certain bacteria and fungi.
Synthesis and Application DMQ can be synthesized through a number of different methods, including the Vilsmeier-Haack reaction, the Ullmann reaction, and the Fischer indole synthesis. The Vilsmeier-Haack reaction involves the reaction of dimethoxybenzaldehyde and dimethylformamide in the presence of phosphorus oxychloride to form a quinolinone intermediate. This intermediate can then be further reacted with a variety of reagents to form DMQ. The Ullmann reaction involves the reaction of an aryl halide with an aryl amine, followed by the reduction of the intermediate with a reducing agent such as sodium borohydride. The Fischer indole synthesis involves the reaction of an aryl halide with an aryl amine in the presence of a palladium catalyst to form an indole intermediate, which can then be further reacted with a variety of reagents to form DMQ. DMQ has been studied for its potential therapeutic applications in a variety of diseases. It has been found to be effective in treating several types of cancer, including lung, breast, and colon cancer. DMQ has also been studied for its potential to inhibit the growth of certain bacteria and fungi, as well as its ability to reduce inflammation and oxidative stress. In addition, DMQ has been studied for its potential to reduce the toxicity of certain drugs and to enhance their therapeutic efficacy. Furthermore, DMQ has been studied for its potential to protect against damage from radiation and to reduce the risk of cardiovascular disease.
Future Directions Given its potential therapeutic applications, there are a number of potential future directions for research on DMQ. These include further research into its potential to inhibit the growth of certain bacteria and fungi, as well as its ability to reduce inflammation and oxidative stress. In addition, further research could be conducted into its potential to reduce the toxicity of certain drugs and to enhance their therapeutic efficacy. Furthermore, further research could be conducted into its potential to protect against damage from radiation and to reduce the risk of cardiovascular disease.