Product Name:Ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-3-oxobutanoate
IUPAC Name:ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-3-oxobutanoate
| Packing Unit | Available Stock | Price($) | Quantity |
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| CM527140-5g | in stock | ǕɅǧ |
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| Product Overview |
Ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-3-oxobutanoate (ETTOB) is an organic compound belonging to the family of thiadiazoles. It is a versatile compound that has been studied for its potential applications in a variety of fields, including medicinal chemistry, drug discovery, and biochemistry. |
| Synthesis and Application |
Ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-3-oxobutanoate can be synthesized from the reaction of 5-methyl-1,3,4-thiadiazol-2-thiol (MTT) and ethyl 3-oxobutanoate. The reaction is carried out in an acidic medium and the product is obtained in good yield. The reaction proceeds via a nucleophilic substitution mechanism, and the product is isolated as an oil. Ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-3-oxobutanoate has been studied for its potential applications in medicinal chemistry, drug discovery, and biochemistry. It has been used as an inhibitor of the enzyme cyclooxygenase-2 (COX-2), which is involved in the synthesis of prostaglandins and is associated with inflammation and pain. It has also been used as an inhibitor of the enzyme acetylcholinesterase (AChE), which is involved in the breakdown of the neurotransmitter acetylcholine and is associated with muscle contraction and memory formation. In addition, Ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-3-oxobutanoate has been studied for its potential to modulate the activity of the enzyme glutathione-S-transferase (GST), which is involved in the detoxification of xenobiotics and is associated with cancer prevention. |
| Future Directions |
The potential applications of Ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-3-oxobutanoate are numerous and varied. Future research could focus on elucidating its mechanism of action and exploring its potential applications in medicinal chemistry, drug discovery, and biochemistry. Additionally, further research could be done to investigate its potential to modulate the activity of enzymes involved in inflammation, pain, muscle contraction, memory formation, and cancer prevention. Finally, further research could be done to investigate its potential as a therapeutic agent for various diseases and disorders. |
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