Product Name:5-cyano-1H-indazole-3-carboxylic acid

IUPAC Name:5-cyano-1H-indazole-3-carboxylic acid

CAS:885520-03-6
Molecular Formula:C9H5N3O2
Purity:97%
Catalog Number:CM132255
Molecular Weight:187.16

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CM132255-250mg in stock ʼnNJ
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For R&D use only.

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Product Details

CAS NO:885520-03-6
Molecular Formula:C9H5N3O2
Melting Point:-
Smiles Code:O=C(C1=NNC2=C1C=C(C#N)C=C2)O
Density:
Catalog Number:CM132255
Molecular Weight:187.16
Boiling Point:
MDL No:
Storage:Store at 2-8°C.

Category Infos

Indazoles
Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.

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Product Other Information

Product Overview 5-Cyano-1H-indazole-3-carboxylic acid (5-CNICA) is an organic compound that has recently garnered attention in the scientific community due to its potential utility in a variety of applications. 5-CNICA is a substituted indazole, a heterocyclic aromatic compound composed of a six-membered aromatic ring with a nitrogen atom at the 3-position.
Synthesis Method 5-Cyano-1H-indazole-3-carboxylic acid can be synthesized in a variety of ways, including direct synthesis, condensation reactions, and oxidative coupling. Direct synthesis is the simplest and most commonly used method, and involves the reaction of 5-chloro-1H-indazole-3-carboxylic acid with potassium cyanide in the presence of a base. Condensation reactions involve the reaction of 5-chloro-1H-indazole-3-carboxylic acid with an aldehyde or ketone. Oxidative coupling involves the reaction of 5-chloro-1H-indazole-3-carboxylic acid with an oxidizing agent such as sodium nitrite or potassium permanganate.
Chemical Properties It is relatively low cost and its availability in a variety of forms. 5-Cyano-1H-indazole-3-carboxylic acid is a highly reactive compound and can undergo a variety of side reactions, which can lead to the formation of unwanted byproducts. It is a hazardous compound and should be handled with care.
Synthesis and Application 5-Cyano-1H-indazole-3-carboxylic acid has been studied for its potential as a pharmaceutical intermediate, and has been used in the synthesis of a variety of compounds with potential applications in the treatment of cancer, inflammation, and other diseases. It has also been used in the synthesis of fluorescent probes, which can be used to detect and image biological targets. It has also been used in the synthesis of a variety of compounds with potential applications in organic electronics and optoelectronics.
Future Directions One possible future direction is the development of new fluorescent probes based on 5-Cyano-1H-indazole-3-carboxylic acid for use in imaging biological targets. Another possible future direction is the development of new pharmaceutical intermediates based on 5-Cyano-1H-indazole-3-carboxylic acid for use in the synthesis of drugs with potential therapeutic applications. It could be used in the synthesis of compounds with potential applications in organic electronics and optoelectronics. Finally, it could be used in the development of new catalysts for use in organic synthesis.