Product Name:3-(3,5-Dichlorophenyl)-1,3-diazaspiro[4.5]decane-2,4-dione

IUPAC Name:3-(3,5-dichlorophenyl)-1,3-diazaspiro[4.5]decane-2,4-dione

CAS:88808-34-8
Molecular Formula:C14H14Cl2N2O2
Purity:97%
Catalog Number:CM218146
Molecular Weight:313.18

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Product Details

CAS NO:88808-34-8
Molecular Formula:C14H14Cl2N2O2
Melting Point:-
Smiles Code:O=C(N1C2=CC(Cl)=CC(Cl)=C2)NC3(CCCCC3)C1=O
Density:
Catalog Number:CM218146
Molecular Weight:313.18
Boiling Point:
MDL No:
Storage:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.
Imidazolidines
Imidazolidine is a heterocyclic compound (CH2)2(NH)2CH2. The parental imidazolidines are less studied, but related compounds substituted on one or both nitrogen centers are more common. Generally, they are colorless, polar, basic compounds. Imidazolidines are examples of cyclic 5-membered general amines. Imidazolidine derivatives are key components in the development of bioactive compounds for the treatment of various diseases, especially Chagas disease. In fact, other studies have shown that imidazoline-2,4-diones have a wide range of pharmacological activities, including anticonvulsant, antiarrhythmic, and antiparasitic.
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