Product Name:4-Chloro-2-cyclopropylquinazoline

IUPAC Name:4-chloro-2-cyclopropylquinazoline

CAS:898044-61-6
Molecular Formula:C11H9ClN2
Purity:95%+
Catalog Number:CM464053
Molecular Weight:204.66

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CM464053-250mg in stock Ǹǟ
CM464053-1g in stock ŽŌŽ
CM464053-5g in stock ǸǸř

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Product Details

CAS NO:898044-61-6
Molecular Formula:C11H9ClN2
Melting Point:-
Smiles Code:ClC1=C2C=CC=CC2=NC(=N1)C1CC1
Density:
Catalog Number:CM464053
Molecular Weight:204.66
Boiling Point:
MDL No:MFCD14453157
Storage:

Category Infos

Quinazolines
Quinazolines belong to heterocyclic chemistry, also known as 1,3-naphthalenes. The backbone consists of two six-membered aromatic rings fused to each other, with two nitrogen atoms at positions 1 and 3 on the backbone. The presence of these two nitrogen atoms in quinazoline increases its importance in pharmaceutical and biological reactions. Quinazolines and their derivatives are among the most important heterocyclic compounds due to their diverse chemical reactivity and important range of biological activities.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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