Product Name:(S)-N,N'-Dimethyl-1,1'-binaphthyldiamine
IUPAC Name:N2,N2'-dimethyl-[1,1'-binaphthalene]-2,2'-diamine
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Product Overview |
(S)-N,N'-Dimethyl-1,1'-binaphthyldiamine, or (S)-Binaphthyl-2,2'-diamine, is a chiral diamine that is used in a variety of synthetic organic chemistry applications. It is a key intermediate in the synthesis of several drugs, including the anti-inflammatory drug celecoxib, and has been used in the synthesis of a variety of other compounds. In addition to its use in organic synthesis, (S)-Binaphthyl-2,2'-diamine is also used in biochemistry and physiology research, where it is used to study the action and effects of various compounds on biological systems. |
Synthesis and Application |
(S)-Binaphthyl-2,2'-diamine can be synthesized by a variety of methods, including the reaction of 1,1'-binaphthalene-2,2-dicarboxylic acid with a primary amine, such as 2-aminoethanol. This reaction produces a mixture of the two diastereomeric forms of (S)-Binaphthyl-2,2'-diamine, which can be separated by chromatographic methods. In addition, (S)-Binaphthyl-2,2'-diamine can also be synthesized by the reaction of 1,1'-binaphthalene-2,2-dicarboxylic dichloride with a primary amine. (S)-Binaphthyl-2,2'-diamine has a variety of scientific research applications. It is used in the synthesis of a variety of compounds, including drugs and other organic compounds. In addition, it is also used in biochemistry and physiology research, where it is used to study the action and effects of various compounds on biological systems. For example, (S)-Binaphthyl-2,2'-diamine has been used to study the enzyme-catalyzed epimerization of 2-amino-1-naphthoic acid, and the effect of the compound on the activity of the enzyme. It has also been used to study the effects of various compounds on the activity of the enzyme cyclooxygenase-2 (COX-2). |
Future Directions |
There are several possible future directions for the use of (S)-Binaphthyl-2,2'-diamine. First, it could be used to study the effects of various compounds on other enzymes, such as proteases, kinases, and phosphatases. Second, it could be used to study the effects of various compounds on other biological systems, such as cells and tissues. Third, it could be used to study the effects of various compounds on the metabolism of drugs. Fourth, it could be used to study the effects of various compounds on the immune system. Finally, it could be used to study the effects of various compounds on the development and progression of diseases. |