Product Name:N-(2-chloro-5-{6-methoxyimidazo[1,2-b]pyridazin-2-yl}phenyl)-2-oxo-2H-chromene-3-carboxamide

IUPAC Name:N-(2-chloro-5-{6-methoxyimidazo[1,2-b]pyridazin-2-yl}phenyl)-2-oxo-2H-chromene-3-carboxamide

CAS:946268-73-1
Molecular Formula:C23H15ClN4O4
Purity:95%+
Catalog Number:CM645333
Molecular Weight:446.85

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Product Details

CAS NO:946268-73-1
Molecular Formula:C23H15ClN4O4
Melting Point:-
Smiles Code:COC1=NN2C=C(N=C2C=C1)C1=CC(NC(=O)C2=CC3=CC=CC=C3OC2=O)=C(Cl)C=C1
Density:
Catalog Number:CM645333
Molecular Weight:446.85
Boiling Point:
MDL No:
Storage:

Category Infos

Coumarins
Coumarin occurs naturally in a variety of plants, such as lentils, sweet sawdust, vanilla grass, and sweet grass. Coumarin has a simple structure, benzopyrone, associated with different reaction centers. Coumarins are further subdivided into different classes: simple coumarins, pyranocoumarins, furanocoumarins, dicoumarins and isocoumarins. Coumarin derivatives are an important class of natural plant metabolites with various biological activities. They can also be synthesized artificially, and various synthetic coumarin derivatives (azoles, sulfonyls, furans, pyrazoles, etc.) have shown good anticancer, antitumor and antiproliferative activities. Coumarin derivatives are not only effective anticancer agents, but also possess minimum side effects. Based on different substitution patterns, these potential active substances show a great ability to modulate potential anticancer activities.
Imidazopyridazines
Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.