Product Name:N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine

IUPAC Name:N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine

CAS:1421372-94-2
Molecular Formula:C20H16FN5O3
Purity:95%+
Catalog Number:CM147323
Molecular Weight:393.38

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Product Details

CAS NO:1421372-94-2
Molecular Formula:C20H16FN5O3
Melting Point:-
Smiles Code:CN1C=C(C2=NC(NC3=CC([N+]([O-])=O)=C(F)C=C3OC)=NC=C2)C4=C1C=CC=C4
Density:
Catalog Number:CM147323
Molecular Weight:393.38
Boiling Point:
MDL No:MFCD28167946
Storage:Keep in dark place, store at 2-8°C.

Column Infos

Indoles
Indole is a compound of pyrrole and benzene in parallel, also known as benzopyrrole. There are two combinations of pyrrole and benzene, called indole and isoindole, respectively. Many derivatives of indole have physiological and pharmacological activities, and can synthesize vasodilators, antihistamines, antipyretic analgesics, etc. in medicine, so indole is also a very important heterocyclic compound.
Osimertinib
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TAGRISSO (osimertinib) is a third-generation, irreversible EGFR-TKI with proven clinical activity in NSCLC, including against central nervous system metastases. It is the first and only EGFR TKI recommended by NCCN Guidelines as an adjuvant treatment option for completely resected stage IB-IIIA, stage IIIB (T3, N2) EGFRm (exon 19 deletion, exon 21 L858R mutation) NSCLC.