Product Name:7-fluoro-1,2,3,4-tetrahydroacridine-9-carboxylic acid

IUPAC Name:7-fluoro-1,2,3,4-tetrahydroacridine-9-carboxylic acid

CAS:727-74-2
Molecular Formula:C14H12FNO2
Purity:95%+
Catalog Number:CM377090
Molecular Weight:245.25

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Product Details

CAS NO:727-74-2
Molecular Formula:C14H12FNO2
Melting Point:-
Smiles Code:OC(=O)C1=C2CCCCC2=NC2=CC=C(F)C=C12
Density:
Catalog Number:CM377090
Molecular Weight:245.25
Boiling Point:
MDL No:
Storage:

Category Infos

Acridines
Acridines are organic compounds and nitrogen heterocycles having the formula C13H9N. Acridine is a substituted derivative of the parent ring. It is a planar molecule structurally related to anthracene in which one carbon in the central CH group is replaced by nitrogen. Acridine and its derivatives can be used to make dyes and also used in the pharmaceutical industry. Acridine is a DNA intercalator that easily binds to DNA. Due to its DNA-intercalating properties, acridine or its suitable derivatives are expected to preferentially accumulate in tumors, which are always associated with enhanced DNA replication. Therefore, radiolabeled acridines may have prospect in tumor imaging.

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Product Other Information

Product Overview 7-Fluoro-1,2,3,4-tetrahydro-acridine-9-carboxylic acid, or 7-FTHA, is an organic compound with a wide range of applications in the scientific research community. It is a derivative of acridine, an aromatic heterocyclic compound, and contains a fluoro group attached to the ring.
Synthesis Method First, the 1-fluoro-4-chloro-2,3-dihydro-1H-acridine is reacted with sodium hydroxide to form 1-fluoro-4-chloro-2-ethoxy-3-hydroxy-1H-acridine. This is then reacted with sodium borohydride to form the desired 7-FTHA. The entire reaction can be carried out in a single step using a palladium-catalyzed reaction.
Chemical Properties First, it is relatively easy to synthesize and is relatively stable. Additionally, it is relatively non-toxic, making it safe to use in experiments. It has a relatively short half-life, meaning that it must be used quickly after synthesis. Additionally, it is not always possible to obtain consistent results with 7-FTHA, as the compound can be affected by a variety of factors, such as temperature and pH.
Synthesis and Application It has been used in the development of drugs for the treatment of cancer, as well as for the study of the biochemical and physiological effects of drugs. It has also been used in the study of the mechanisms of action of various drugs, as well as the study of the pharmacokinetics of drugs. Additionally, it has been used in the study of the metabolism of drugs, as well as in the study of the pharmacodynamics of drugs.
Future Directions First, it could be used as a tool to study the mechanisms of action of various drugs. Additionally, it could be used to study the pharmacokinetics and pharmacodynamics of drugs, as well as the metabolism of drugs. Additionally, it could be used to study the biochemical and physiological effects of drugs, as well as to develop new drugs for the treatment of various diseases. Finally, it could be used to study the effects of environmental toxins on the body, as well as to develop new methods of drug delivery.